Sinugard Granules – Unani answer to Paranasal sinuses Reviewed by Momizat on . HERBAL CHIKITSA A study carried out to evaluate the efficacy of Unani formulation ‘Sinugard Granules’ in mucosal inflammation of the Paranasal sinuses concluded HERBAL CHIKITSA A study carried out to evaluate the efficacy of Unani formulation ‘Sinugard Granules’ in mucosal inflammation of the Paranasal sinuses concluded Rating: 0
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Sinugard Granules – Unani answer to Paranasal sinuses

Sinugard Granules – Unani answer to Paranasal sinuses

HERBAL CHIKITSA
A study carried out to evaluate the efficacy of Unani formulation ‘Sinugard Granules’ in mucosal inflammation of the Paranasal sinuses concluded that the compound Unani formulation ‘Sinugard Granules’ is very useful in treating the medical condition. It revealed that the Unani formulation gives good response on nasal congestion, tenderness and nasal discharge.

Paranasal sinuses (Warm-e-Tajaweef-e-Anf) is an acute or chronic process which is generally followed by an attack of acute rhinitis as in common cold or influenza when the bacteria invade as secondary organisms.

Paranasal sinuses are air-containing cavities in certain bones of skull. They are four on each side. Paranasal sinuses are lined by mucous membrane which is continuous with that of the nasal cavity through the ostia of sinuses. Paranasal sinuses develop as outpouchings from the mucous membrane of lateral wall of nose (Maqbool, 2002).

Though several allopathic drugs are available to treat the sinusitis but their use is hindered by adverse effects of such drugs. Therefore, we felt the necessity to find an alternative treatment in Indian system of Medicine, which could be used for a prolong interval of time without any serious complication.

In ancient Unani literature, Warm-e-Tajaweef-e-Anf (sinusitis) is not described as such but when we go through the definitions of Nazla wa Zukam (Coryza or common cold) these seem to be quite similar to the clinical features of sinusitis (Arzani, 1956). Therefore, while laid down the principles of treatment of Warm- e-Tajaweef-e-Anf we may take etiopathogenesis of Nazla wa Zukam into consideration and treat this condition accordingly.

The study was open single group uncontrolled clinical trial in which 40 persons of 13 to 57 years of age were enrolled for 10 days from Moalejat and Otorhinolaryngology OPD, Ajmal Khan Tibbiya College, Aligarh Muslim University, Aligarh. The patients, who were clinically diagnosed with Paranasal sinuses and complained of headache, facial pain, tenderness, nasal discharge and nasal congestion, were treated with half sachet of ‘Sinugard Granules’ twice a day with lukewarm water.

The patients subjected to the clinical trial were given half sachet of SINUGARD GRANULES twice a day for a period of 10 days. The patients were followed on every 5th day.

Each sachet of SINUGARD contains 2 grams of granules and has following ingredients.
Quantity
550 mg 550 mg 550 mg 60 mg 40 ml 250 mg
Name of ingredient
Lavandula stoechas L. (Ustukhuddus)
Glycyrrhiza glabra L. (Asalassus)
Foeniculum vulgare Mill. (Badiyan)
Menthol Eucalyptus oil Cane sugar
Results and Observations

There was significant improvement in the subjective parameters except in the headache and facial pain.
During the study, patients were divided into five age groups viz. 13-21 years, 22-30 years, 31-39 years, 40-48 years, 49-57 years. It was observed that maximum number of cases i.e. 14 cases (35.0 per cent) belong to the age group 13-21 years. 13 cases (32.5 per cent) fell in the age group 22-30 years, 4 cases (10.0 per cent) in the age group 31-39 years, 6 cases (15.0 per cent) in the age group 40-48 years and 3 cases (7.5 per cent) in the age group 49-57 years.

Of the 40 patients, 25 (62.5 per cent) were males, while 15 cases (37.5 per cent) were females. They were divided into five categories according to their occupation, student, service, labour, business and housewife. The number of cases falling in each category was 16 (40 per cent), 6(15 per cent), 5 (12.5 per cent), 4(10.0 per cent) and 9 (22.5 per cent) respectively. Thus it was observed that maximum number of patients belong to students followed by housewives and service class.
The patients were divided into three groups on the basis of site of infection, frontal, maxillary, frontal and maxillary both. Maximum cases were found of frontal sinusitis i.e. 27 cases (67.5 per cent) followed by 7 cases (17.5 per cent) of maxillary sinusitis and 6 cases (15.0 per cent) of frontal accompanied with maxillary sinusitis.

The subjective parameters viz. headache, facial pain, tenderness, nasal discharge and nasal congestion were taken into consideration during the study. Out of 40 cases, facial pain, tenderness, nasal discharge and nasal congestion was found in 32 cases, 26 cases, 28 cases and 9 cases respectively, while headache was the main complaint in all the cases. At the end of study, it was observed that headache, facial pain, tenderness, nasal discharge and nasal congestion was improved by 57.5 per cent (23 cases), 53.12 per cent (17 cases), 69.23 per cent (18 cases), 67.85 per cent (19 cases) and 77.77 per cent (7 cases) respectively.

At the end of study, maximum benefit was observed in the Nasal congestion i.e. 77.77% improvement. Anti-inflammatory property of Ustukhuddus (Baghdadi, 2005, Hakim, 1924, Anonymous, 1992) and Aslusoos (Kritkar, Basu, 1996) may be attributed to this effect of drug. Glycyrrhizin inhibited thrombin induced platelet aggregation which indicates anti-inflammatory activity (www.krishnaherbals.com).

Nasal congestion was also improved due to the presence of menthol in the formulation because most of menthol’s uses are related to its stimulation of the cold receptors. This property makes menthol to produce a cooling effect, which help to relieve the congestion (www.wisegeek. com). Moreover, it is used in pharmaceutical preparations to disguise the taste of evil-smelling and unpleasant drugs (Chopra, 1958).

There was 67.85 per cent improvement in the patients of Nasal discharge, which may be due to the antiseptic property of Ustukhuddus (Ahmad, 1985), Aslusoos (Rastogi, 1985-89) and eucalyptus oil. Cineole (eucalyptol) is the most important ingredient of eucalyptol oil from the medical point of view. Australol and cryptol have also been found to be efficient antiseptic (Chopra, 1958).
The headache, facial pain and tenderness were improved by 57.5C 53.12% and 69.23% respectively at the end of study. Analgesic property Ustukhuddus, Aslusoos and Badiyan may be attributed to this effect of dri (Anonymous, 1998, Gazrooni, 1887).

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